Article
Impaired monocyte-derived dendritic cell phenotype in prostate cancer patients: A phenotypic comparison with healthy donors.
Cancer reports (Hoboken, N.J.) - 1 Feb 2024
Bakhshi Parisa, Nourizadeh Maryam, Sharifi Laleh, Nowroozi Mohammad R, Mohsenzadegan Monireh, Farajollahi Mohammad M
Abstract excerpt
BACKGROUND: Dendritic cells (DCs) play a crucial role in immunity. Research on monocyte-derived DCs (Mo-DCs) cancer vaccines is in progress despite limited success in clinical trials. This study focuses on Mo-DCs generated from prostate cancer (PCA) patients, comparing them with DCs from healthy donors (HD-DCs). METHODS: Mo-DCs were isolated from PCA patient samples, and their phenotype was compared to HD-DCs....
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