Article
Phenotype and antitumor activity of ascitic fluid monocytes in patients with ovarian carcinoma.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jan 2000
Melichar B, Savary C A, Patenia R, Templin S, Melicharova K, Freedman R S
Abstract excerpt
Monocytes/macrophages (MO/MA) represent a major leukocyte population in the peritoneal cavity of patients with epithelial ovarian cancer (EOC). We examined the phenotypic characteristics and antitumor cell activity of ascitic MO in patients with EOC. MO/MA phenotype was compared with MO in peripheral blood by two- and three-color flow cytometry. Cytotoxic/cytostatic effects of different cytokines on cultured EOC...
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