Article
Characterization of blood monocyte phenotype in patients with endometrial cancer.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Nov 2012
Brooks Nicole, Stojanovska Lily, Grant Peter, Apostolopoulos Vasso, McDonald Christine F, Pouniotis Dodie S
Abstract excerpt
BACKGROUND: Endometrial tumors induce various tumor escape mechanisms that result in immunosuppression in patients and, ultimately, tumor progression. Blood monocytes are able to exhibit potent cytotoxic action against tumor cells where novel immunotherapeutics targeting antigen-presenting cells including dendritic cells, and blood monocytes are being used as a means of delivering immunogens to stimulate an...
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