Article
Interactions between osteosarcoma cell lines and dendritic cells immune function: An in vitro study.
Cellular immunology - 1 Jan 2000
Muraro Michela, Mereuta Oana M, Saglio Francesco, Carraro Francesca, Berger Massimo, Madon Enrico, Fagioli Franca
Abstract excerpt
Dendritic cells (DCs) might be partly responsible for the defective immune response in tumor bearing hosts, but no study in osteosarcoma patients is still available. Therefore, we investigated in vitro whether human osteosarcoma cell lines have an inhibitor effect on different types of DCs: CD14+DCs, DC1 and DC2. DCs derived from healthy donors were cultured with osteosarcoma cell lines and appropriate cytokine...
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