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MicroRNAs Are Stored in Human MII Oocyte and Their Expression Profile Changes in Reproductive Aging

9 Nov 2016

Abstract excerpt

Maternal RNAs are synthesized by the oocyte during its growth; some of them are utilized for oocyte-specific processes and metabolism, others are stored and used during early development before embryonic genome activation. The appropriate expression of complex sets of genes is needed for oocyte maturation and early embryo development. In spite of the basic role of noncoding RNAs in the regulation of gene...

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PMID: 28007692
DOI: 10.1095/biolreprod.116.142711

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