Article
CD4+ T cells and Lactobacillus casei control relapsing colitis mediated by CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 2009
Hacini-Rachinel Feriel, Nancey Stephane, Boschetti Gilles, Sardi Fatima, Doucet-Ladevèze Remi, Durand Pierre-Yves, Flourié Bernard, Kaiserlian Dominique
Abstract excerpt
Evidence that CD4(+) regulatory T cells can control Ag-specific CD8(+) T cell-mediated colitis in immunocompetent mice is poorly documented. To examine the potential of CD4(+) T cells to control colitis, we used our model of CD8(+) T cell-mediated colitis induced by intracolonic sensitization followed by challenge with the hapten 2,4-dinitrobenzene sulfonic acid. The defect of CD4(+) T cells in MHC class...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.