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Article

RORγt+ Treg to Th17 ratios correlate with susceptibility to Giardia infection.

Scientific reports - 30 Dec 2019

Yordanova Ivet A, Cortés Alba, Klotz Christian, Kühl Anja A, Heimesaat Markus M, Cantacessi Cinzia, Hartmann Susanne, Rausch Sebastian

Abstract excerpt

Infections with Giardia are among the most common causes of food and water-borne diarrheal disease worldwide. Here, we investigated Th17, Treg and IgA responses, and alterations in gut microbiota in two mouse lines with varying susceptibility to Giardia muris infection. Infected BALB/c mice shed significantly more cysts compared with C57BL/6 mice. Impaired control of infection in BALB/c mice was associated with...

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Identifiers

PMID: 31889073
DOI: 10.1038/s41598-019-56416-9
PMCID: PMC6937251

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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