Article
Oxidized phospholipids predict the presence and progression of carotid and femoral atherosclerosis and symptomatic cardiovascular disease: five-year prospective results from the Bruneck study.
Journal of the American College of Cardiology - 6 Jun 2006
Tsimikas Sotirios, Kiechl Stefan, Willeit Johann, Mayr Manuel, Miller Elizabeth R, Kronenberg Florian, Xu Qingbo, Bergmark Claes, Weger Siegfried, Oberhollenzer Friedrich, Witztum Joseph L
Abstract excerpt
OBJECTIVES: The purpose of this work was to determine the predictive value of oxidized phospholipids (OxPLs) present on apolipoprotein B-100 particles (apoB) in carotid and femoral atherosclerosis. BACKGROUND: The OxPLs are pro-inflammatory and pro-atherogenic and may be detected using the antibody E06 (OxPL/apoB). METHODS: The Bruneck study is a prospective population-based survey of 40- to 79-year-old men and...
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