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Article

BRCA promoter methylation in sporadic versus BRCA germline mutation-related breast cancers.

Breast cancer research : BCR - 31 May 2017

Vos Shoko, Moelans Cathy Beatrice, van Diest Paul Joannes

Abstract excerpt

BACKGROUND: In breast cancer, BRCA promoter hypermethylation and BRCA germline mutations are said to occur together rarely, but this property has not yet been translated into a clinical test. Our aim in this study was to investigate the diagnostic value of BRCA1/2 methylation in distinguishing breast carcinomas of BRCA1 and BRCA2 germline mutation carriers from sporadic breast carcinomas using a recently...

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Share to CpG Islands
Share to DNA Methylation
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Genes, BRCA1

Share to Genes, BRCA2

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Source

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Identifiers

PMID: 28569220
DOI: 10.1186/s13058-017-0856-z
PMCID: PMC5452400

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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