Article
Correlation of PICALM polymorphism rs3851179 with Alzheimer's disease among Caucasian and Chinese populations: a meta-analysis and systematic review.
Metabolic brain disease - 1 Dec 2018
Zhu Bin, Li Li-Xia, Zhang Lei, Yang Shu, Tian Yue, Guo Shan-Shan, Zhang Wei, Zhao Zhi-Gang
Abstract excerpt
The rs3851179 which located at upstream of PICALM was reported to be associated with Alzheimer's disease (AD); however, the relationship is still undefined. To gain a more precise understanding of the association, we conducted a meta-analysis: a comprehensive survey of 16 case-control studies that evaluated the role of rs3851179 gene variants in AD patients. The overall analysis revealed a significant association...
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