Article
Genotyping Analysis of Bitter-Taste Receptor Genes TAS2R38 and TAS2R46 in Japanese Patients with Gastrointestinal Cancers.
Journal of nutritional science and vitaminology - 1 Jan 2017
Yamaki Michiko, Saito Hiroki, Isono Kunio, Goto Tomoko, Shirakawa Hitoshi, Shoji Noriaki, Satoh-Kuriwada Shizuko, Sasano Takashi, Okada Ryo, Kudoh Katsuyoshi, Motoi Fuyuhiko, Unno Michiaki, Komai Michio
Abstract excerpt
Type-2 bitter-taste receptors (TAS2Rs) are important for the evaluation of food quality and the nutritional control in animals. Mutations in some TAS2Rs including TAS2R38 are known to increase susceptibility to various diseases. However, the involvement of TAS2Rs in cancers has not been well understood. We conducted a pilot study by genotyping two TAS2R genes, TAS2R38 and TAS2R46, in Japanese cancer patients...
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