Article
Multiplex minisequencing screening for PTC genotype associated with bitter taste perception.
Molecular biology reports - 1 Mar 2014
Sagong Borum, Bae Jae Woong, Rhyu Mee Ra, Kim Un-Kyung, Ye Mi-Kyung
Abstract excerpt
Sensitivity to phenylthiocarbamide (PTC) has a bimodal distribution pattern and the genotype of the TAS2R38 gene, which is composed of combinations of three coding single nucleotide polymorphisms (SNPs), p.A49P (c.145G>C), p.V262A (c.785T>C) and p.I296 V (c.886A>G), determines the ability or inability to taste PTC. In this study, we developed a tool for genotyping of these SNPs in the TAS2R38 gene using SNaPshot...
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