Article
Genetic Variation in the TAS2R38 Bitter Taste Receptor and Smoking Behaviors.
PloS one - 1 Jan 2016
Risso Davide S, Kozlitina Julia, Sainz Eduardo, Gutierrez Joanne, Wooding Stephen, Getachew Betelihem, Luiselli Donata, Berg Carla J, Drayna Dennis
Abstract excerpt
Common TAS2R38 taste receptor gene variants specify the ability to taste phenylthiocarbamide (PTC), 6-n-propylthiouracil (PROP) and structurally related compounds. Tobacco smoke contains a complex mixture of chemical substances of varying structure and functionality, some of which activate different taste receptors. Accordingly, it has been suggested that non-taster individuals may be more likely to smoke because...
Topics
- Adult
- Black or African American
- Cohort Studies
- Female
- Genetic Variation
- Haplotypes
- Humans
- Male
- Middle Aged
- Phenylthiourea
- Receptors, G-Protein-Coupled