Genetic Variation in the TAS2R38 Bitter Taste Receptor and Gastric Cancer Risk in Koreans.

doi:10.1038/srep26904

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Article

Genetic Variation in the TAS2R38 Bitter Taste Receptor and Gastric Cancer Risk in Koreans.

Scientific reports - 1 Jun 2016

Choi Jeong-Hwa, Lee Jeonghee, Choi Il Ju, Kim Young-Woo, Ryu Keun Won, Kim Jeongseon

Abstract excerpt

The human TAS2R38 gene encodes a bitter taste receptor that regulates the bitterness perception and differentiation of ingested nutritional/poisonous compounds in the oral cavity and gastrointestinal tract. TAS2R38 gene variants are associated with alterations in individual sensitivity to bitter taste and food intake; hence, these genetic variants may modify the risk for diet-related diseases, including cancer....

Topics

Adult
Aged
Alcohol Drinking
Asian People
Aversive Agents
Case-Control Studies
Dietary Carbohydrates
Dietary Fiber
Eating
Female
Fruit
Gene Expression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Humans

Male

Middle Aged

Phenotype

Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 27245112
DOI: 10.1038/srep26904
PMCID: PMC4887993

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-27245112-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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