Article
APOL1 genetic variants are not associated with longitudinal blood pressure in young black adults.
Kidney international - 1 Oct 2017
Chen Teresa K, Estrella Michelle M, Vittinghoff Eric, Lin Feng, Gutierrez Orlando M, Kramer Holly, Lewis Cora E, Kopp Jeffrey B, Allen Norrina B, Winkler Cheryl A, Bibbins-Domingo Kirsten B, Peralta Carmen A
Abstract excerpt
Whether APOL1 polymorphisms contribute to the excess risk of hypertension among blacks is unknown. To assess this we evaluated whether self-reported race and, in blacks, APOL1 risk variants (high-risk [2 risk alleles] versus low-risk [0-1 risk allele]) were associated with longitudinal blood pressure. Blood pressure trajectories were determined using linear mixed-effects (slope) and latent class models...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
