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Article

APOL1 Risk Variants, Incident Proteinuria, and Subsequent eGFR Decline in Blacks with Hypertension-Attributed CKD.

Clinical journal of the American Society of Nephrology : CJASN - 7 Nov 2017

Chen Teresa K, Tin Adrienne, Peralta Carmen A, Appel Lawrence J, Choi Michael J, Lipkowitz Michael S, Winkler Cheryl A, Estrella Michelle M

Abstract excerpt

BACKGROUND AND OBJECTIVES: The natural history of kidney disease among blacks who carry the APOL1 high-risk variants varies, with only a subgroup progressing to ESRD. We aimed to determine whether the APOL1 risk variants are associated with incident proteinuria in the context of hypertension-attributed CKD, and whether subsequent kidney function decline after the onset of proteinuria differs by APOL1 risk status....

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Share to Apolipoprotein L1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Creatinine

Share to Glomerular Filtration Rate

Share to Hypertension

Share to Proportional Hazards Models

Share to Proteinuria

Share to Renal Insufficiency, Chronic

Source

Open in PubMed Open full text

Identifiers

PMID: 29051146
DOI: 10.2215/CJN.01180117
PMCID: PMC5672963

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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