Article
Examination of Potential Modifiers of the Association of APOL1 Alleles with CKD Progression.
Clinical journal of the American Society of Nephrology : CJASN - 7 Dec 2015
Chen Teresa K, Choi Michael J, Kao W H Linda, Astor Brad C, Scialla Julia J, Appel Lawrence J, Li Liang, Lipkowitz Michael S, Wolf Myles, Parekh Rulan S, Winkler Cheryl A, Estrella Michelle M, Crews Deidra C
Abstract excerpt
BACKGROUND AND OBJECTIVES: Common apolipoprotein L1 (APOL1) variants are associated with increased risk of progressive CKD; however, not all individuals with high-risk APOL1 variants experience CKD progression. Identification of factors contributing to heterogeneity has important scientific and clinical implications. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Using multivariable Cox models, we analyzed data...
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