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Association of APOL1 Risk Alleles With Cardiovascular Disease in Blacks in the Million Veteran Program

24 Jul 2019

Abstract excerpt

Background: Approximately 13% of black individuals carry 2 copies of the apolipoprotein L1 ( APOL1 ) risk alleles G1 or G2, which are associated with 1.5- to 2.5-fold increased risk of chronic kidney disease. There have been conflicting reports as to whether an association exists between APOL1 risk alleles and cardiovascular disease (CVD) that is independent of the effects of APOL1 on kidney disease. We sought to...

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PMID: 31337231
DOI: 10.1161/circulationaha.118.036589

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