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Article

Race, APOL1 Risk, and eGFR Decline in the General Population.

Journal of the American Society of Nephrology : JASN - 1 Sept 2016

Grams Morgan E, Rebholz Casey M, Chen Yuan, Rawlings Andreea M, Estrella Michelle M, Selvin Elizabeth, Appel Lawrence J, Tin Adrienne, Coresh Josef

Abstract excerpt

The APOL1 high-risk genotype, present in approximately 13% of blacks in the United States, is a risk factor for kidney function decline in populations with CKD. It is unknown whether genetic screening is indicated in the general population. We evaluated the prognosis of APOL1 high-risk status in participants in the population-based Atherosclerosis Risk in Communities (ARIC) study, including associations with eGFR...

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Source

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Identifiers

PMID: 26966015
DOI: 10.1681/ASN.2015070763
PMCID: PMC5004654

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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