Article
APOL1 risk variants, race, and progression of chronic kidney disease.
The New England journal of medicine - 5 Dec 2013
Parsa Afshin, Kao W H Linda, Xie Dawei, Astor Brad C, Li Man, Hsu Chi-yuan, Feldman Harold I, Parekh Rulan S, Kusek John W, Greene Tom H, Fink Jeffrey C, Anderson Amanda H, Choi Michael J, Wright Jackson T, Lash James P, Freedman Barry I, Ojo Akinlolu, Winkler Cheryl A, Raj Dominic S, Kopp Jeffrey B, He Jiang, Jensvold Nancy G, Tao Kaixiang, Lipkowitz Michael S, Appel Lawrence J
Abstract excerpt
BACKGROUND: Among patients in the United States with chronic kidney disease, black patients are at increased risk for end-stage renal disease, as compared with white patients. METHODS: In two studies, we examined the effects of variants in the gene encoding apolipoprotein L1 (APOL1) on the progression of chronic kidney disease. In the African American Study of Kidney Disease and Hypertension (AASK), we evaluated...
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