Article
Strict blood pressure control associates with decreased mortality risk by APOL1 genotype.
Kidney international - 1 Feb 2017
Ku Elaine, Lipkowitz Michael S, Appel Lawrence J, Parsa Afshin, Gassman Jennifer, Glidden David V, Smogorzewski Miroslaw, Hsu Chi-Yuan
Abstract excerpt
Although APOL1 high-risk genotype partially accounts for the increased susceptibility of blacks to chronic kidney disease (CKD), whether APOL1 associates differentially with mortality risk remains controversial. Here we evaluate the association between APOL1 genotype and risk of death and determine whether APOL1 status modifies the association between strict versus usual blood pressure control and mortality risk....
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