Article
Association of APOL1 Genotypes With Measures of Microvascular and Endothelial Function, and Blood Pressure in MESA.
Journal of the American Heart Association - 1 Sept 2020
Chen Teresa K, Katz Ronit, Estrella Michelle M, Post Wendy S, Kramer Holly, Rotter Jerome I, Tayo Bamidele, Mychaleckyj Josyf C, Wassel Christina L, Peralta Carmen A
Abstract excerpt
Background APOL1 high-risk genotypes are associated with increased risk for hypertension-attributed kidney disease among Black adults in the United States. Biopsy studies show differences in kidney vasculature by APOL1 status; less is known about the variants' associations with systemic vascular and endothelial function. Whether APOL1 risk variants are associated with blood pressure (BP) is also uncertain....
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