Article
Race, APOL1 Risk Variants, and Clinical Outcomes among Older Adults: The ARIC Study.
Journal of the American Geriatrics Society - 1 Jan 2021
Chen Teresa K, Coresh Josef, Daya Natalie, Ballew Shoshana H, Tin Adrienne, Crews Deidra C, Grams Morgan E
Abstract excerpt
BACKGROUND/OBJECTIVES: APOL1 high-risk genotypes confer an increased risk for kidney disease, but their clinical significance among older adults remains unclear. We aimed to determine whether APOL1 genotype status (high risk = 2 risk alleles; low risk = 0-1 risk alleles) and self-reported race (Black; White) are associated with number of hospitalizations, incident chronic kidney disease (CKD), end-stage renal...
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