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Article

The Individual and Population Genetics of Antibody Immunity.

Trends in immunology - 1 Jul 2017

Watson Corey T, Glanville Jacob, Marasco Wayne A

Abstract excerpt

Antibodies (Abs) produced by immunoglobulin (IG) genes are the most diverse proteins expressed in humans. While part of this diversity is generated by recombination during B-cell development and mutations during affinity maturation, the germ-line IG loci are also diverse across human populations and ethnicities. Recently, proof-of-concept studies have demonstrated genotype-phenotype correlations between specific...

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Share to Antibodies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Loci

Share to Genetics, Population

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Share to Immunity, Humoral

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Identifiers

PMID: 28539189
DOI: 10.1016/j.it.2017.04.003
PMCID: PMC5656258

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