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Article

Untangling associations between immunoglobulin genotypes, repertoires and function.

Immunology letters - 1 Jul 2023

Castro Dopico Xaquin, Mandolesi Marco, Karlsson Hedestam Gunilla B

Abstract excerpt

Immunoglobulin (IG) genes, encoding B cell receptors (BCRs), are fundamental components of the mammalian immune system, which evolved to recognize the diverse antigenic universe present in nature. To handle these myriad inputs, BCRs are generated through combinatorial recombination of a set of highly polymorphic germline genes, resulting in a vast repertoire of antigen receptors that initiate responses to...

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Identifiers

PMID: 37209913
DOI: 10.1016/j.imlet.2023.05.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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