Article
Genome-wide association study of subclinical interstitial lung disease in MESA.
Respiratory research - 18 May 2017
Manichaikul Ani, Wang Xin-Qun, Sun Li, Dupuis Josée, Borczuk Alain C, Nguyen Jennifer N, Raghu Ganesh, Hoffman Eric A, Onengut-Gumuscu Suna, Farber Emily A, Kaufman Joel D, Rabinowitz Dan, Stukovsky Karen D Hinckley, Kawut Steven M, Hunninghake Gary M, Washko George R, O'Connor George T, Rich Stephen S, Barr R Graham, Lederer David J
Abstract excerpt
BACKGROUND: We conducted a genome-wide association study (GWAS) of subclinical interstitial lung disease (ILD), defined as high attenuation areas (HAA) on CT, in the population-based Multi-Ethnic Study of Atherosclerosis Study. METHODS: We measured the percentage of high attenuation areas (HAA) in the lung fields on cardiac CT scan defined as voxels with CT attenuation values between -600 and -250 HU. Genetic...
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