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Article

Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study.

BMC medical genetics - 19 Sept 2007

O'Donnell Christopher J, Cupples L Adrienne, D'Agostino Ralph B, Fox Caroline S, Hoffmann Udo, Hwang Shih-Jen, Ingellson Erik, Liu Chunyu, Murabito Joanne M, Polak Joseph F, Wolf Philip A, Demissie Serkalem

Abstract excerpt

INTRODUCTION: Subclinical atherosclerosis (SCA) measures in multiple arterial beds are heritable phenotypes that are associated with increased incidence of cardiovascular disease. We conducted a genome-wide association study (GWAS) for SCA measurements in the community-based Framingham Heart Study. METHODS: Over 100,000 single nucleotide polymorphisms (SNPs) were genotyped (Human 100K GeneChip, Affymetrix) in...

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Identifiers

PMID: 17903303
DOI: 10.1186/1471-2350-8-S1-S4
PMCID: PMC1995605

Genes

ABI2
ESR1
NOS3
PCSK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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