Relationship between soluble CD25 and gene expression in healthy individuals and patients with multiple sclerosis.

doi:10.1016/j.cyto.2017.04.024

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Relationship between soluble CD25 and gene expression in healthy individuals and patients with multiple sclerosis.

Cytokine - 1 May 2017

Buhelt Sophie, Ratzer Rikke Lenhard, Christensen Jeppe Romme, Börnsen Lars, Sellebjerg Finn, Søndergaard Helle Bach

Abstract excerpt

Genome wide association studies and fine mapping has established a firm link between the IL2RA gene, encoding the interleukin-2 receptor α-chain CD25, and susceptibility to multiple sclerosis (MS). We hypothesized that gene expression in peripheral blood mononuclear cells (PBMCs) from healthy controls (HCs) and MS patients are associated with IL2RA SNP rs2104286 and that gene expression levels correlate with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Expression Profiling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Genome-Wide Association Study

Share to Interleukin-2 Receptor alpha Subunit

Share to Leukocytes, Mononuclear

Share to Multiple Sclerosis

Share to Oligonucleotide Array Sequence Analysis

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 28511943
DOI: 10.1016/j.cyto.2017.04.024

Genes

BCL6
NFKB1
STAT1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relationship between soluble CD25 and gene expression in healthy individuals and patients with multiple sclerosis.PMID 28511943Read ↗

IL2RA Methylation and Gene Expression in Relation to the Multiple Sclerosis-Associated Gene Variant rs2104286 and Soluble IL-2Rα in CD8+ T Cells.Semantic proximity Read ↗

Impact of genetic risk loci for multiple sclerosis on expression of proximal genes in patients.Semantic proximity Read ↗

Genetic and gene expression signatures in multiple sclerosis.Semantic proximity Read ↗

Multiple sclerosis risk variants regulate gene expression in innate and adaptive immune cells.Semantic proximity Read ↗

The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis.Semantic proximity Read ↗

Fingolimod alters the transcriptome profile of circulating CD4+ cells in multiple sclerosisSemantic proximity Read ↗

Genome wide differences of gene expression associated with HLA-DRB1 genotype in multiple sclerosis: a pilot study.Semantic proximity Read ↗

Long-Term Genome-Wide Blood RNA Expression Profiles Yield Novel Molecular Response Candidates for IFN-β-1b Treatment in Relapsing Remitting MSSemantic proximity Read ↗

Genes implicated in multiple sclerosis pathogenesis from consilience of genotyping and expression profiles in relapse and remission.Semantic proximity Read ↗

IL-22RA2 associates with multiple sclerosis and macrophage effector mechanisms in experimental neuroinflammation.Semantic proximity Read ↗

Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells.Semantic proximity Read ↗

Fine mapping of multiple sclerosis susceptibility genes provides evidence of allelic heterogeneity at the IL2RA locus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.