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Article

IL-22RA2 associates with multiple sclerosis and macrophage effector mechanisms in experimental neuroinflammation.

Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 2010

Beyeen Amennai D, Adzemovic Milena Z, Ockinger Johan, Stridh Pernilla, Becanovic Kristina, Laaksonen Hannes, Lassmann Hans, Harris Robert A, Hillert Jan, Alfredsson Lars, Celius Elisabeth G, Harbo Hanne F, Kockum Ingrid, Jagodic Maja, Olsson Tomas

Abstract excerpt

Multiple sclerosis (MS) is an inflammatory neurodegenerative disease of the CNS. Recent advances in whole-genome screening tools have enabled discovery of several MS risk genes, the majority of which have known immune-related functions. However, disease heterogeneity and low tissue accessibility hinder functional studies of established MS risk genes. For this reason, the MS model experimental autoimmune...

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Share to Animals, Congenic
Share to Encephalomyelitis, Autoimmune, Experimental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Immunity, Innate

Share to Macrophages, Peritoneal

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Identifiers

PMID: 21041731
DOI: 10.4049/jimmunol.1001392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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