Article
Molecular Mechanisms Linking Genes and Vitamins of the Complex B Related to One-Carbon Metabolism in Breast Cancer: An In Silico Functional Database Study.
International journal of molecular sciences - 26 Jul 2024
Gálvez-Navas José María, Molina-Montes Esther, Rodríguez-Barranco Miguel, Ramírez-Tortosa MCarmen, Gil Ángel, Sánchez María-José
Abstract excerpt
Carcinogenesis is closely related to the expression, maintenance, and stability of DNA. These processes are regulated by one-carbon metabolism (1CM), which involves several vitamins of the complex B (folate, B2, B6, and B12), whereas alcohol disrupts the cycle due to the inhibition of folate activity. The relationship between nutrients related to 1CM (all aforementioned vitamins and alcohol) in breast cancer has...
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