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Article

Association between NLPR1, NLPR3, and P2X7R Gene Polymorphisms with Partial Seizures.

BioMed research international - 1 Jan 2017

Wang Haidong, Xu Pengfei, Liao Dehua, Dang Ruili, He Xin, Guo Yujin, Jiang Pei

Abstract excerpt

Objectives. Clinical and experimental evidence has clarified that the inflammatory processes within the brain play a pivotal role in the pathophysiology of seizures and epilepsy. Inflammasomes and P2X7 purinergic receptor (P2X7R) are important mediators during the inflammatory process. Therefore, we investigated the possible association between partial seizures and inflammasomes NLPR1, NLRP3, and P2X7R gene...

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Source

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Identifiers

PMID: 28503575
DOI: 10.1155/2017/9547902
PMCID: PMC5414494

Genes

NLRP3
NLRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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