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Article

Correlation between P2X7 receptor gene polymorphisms and gout.

Rheumatology international - 1 Aug 2015

Gong Qiong-Yao, Chen Yong

Abstract excerpt

Not all patients with hyperuricemia will develop acute gouty arthritis, indicating that other initiating factors need to be considered. The P2X7 receptor is an adenosine triphosphate-gated nonselective cation channel that has also been suggested to be a proinflammatory receptor. In the immune system, the P2X7 receptor is involved in the processing and release of various proinflammatory cytokines, including...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25800962
DOI: 10.1007/s00296-015-3258-5

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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