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Article

P2Y12 receptor gene polymorphisms are associated with epilepsy.

Purinergic signalling - 1 Mar 2023

Wang Qi, Shi Nan-Rui, Lv Peng, Liu Juan, Zhang Ji-Zhou, Deng Bin-Lu, Zuo Yan-Qin, Yang Jie, Wang Xin, Chen Xiang, Hu Xiu-Min, Liu Ting-Ting, Liu Jie

Abstract excerpt

The basic research indicated that microglial P2Y12 receptors (P2Y12Rs) are involved in the pathophysiology of epilepsy through regulated microglial-neuronal interactions, aberrant neurogenesis, or immature neuronal projections. However, whether the clinic case of epilepsy would be associated with P2Y12 receptor gene polymorphisms is presented with few data. In our study, a total of 176 patients with epilepsy and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35175489
DOI: 10.1007/s11302-022-09848-4
PMCID: PMC9984642

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