Article
Purinergic P2X7 receptor functional genetic polymorphisms are associated with the susceptibility to obesity in Chinese postmenopausal women.
Menopause (New York, N.Y.) - 1 Mar 2018
Liu Xingzi, Rao Shenqiang, Gong Chengxin, Li Tao, Ding Lu, Wang Shuo, Zhong Peipei, Wang Jihong, Zhao Jiani, Zhou Yuru, Xiong Chaopeng, Tu Yunming, Liang Shangdong, Xu Hong
Abstract excerpt
OBJECTIVE: We conducted a case-control study to investigate the associations of functional single-nucleotide polymorphisms in the purinergic P2X7 receptor (P2X7R) gene (rs2393799, rs7958311, rs1718119, rs2230911, and rs3751143) with obesity and overweight in a population of Chinese postmenopausal women. METHODS: Our study included 180 obese women, 179 overweight women, and 204 controls. All participants were...