Article
Genetic polymorphisms of purinergic P2Y2 receptor were associated with the susceptibility to essential hypertension in Chinese postmenopausal women.
Purinergic signalling - 1 Dec 2023
Li Ao, Xiong Chaopeng, Gong Chengxin, Gou Mengyang, Wang Yaqun, Yang Yuping, Xu Hong
Abstract excerpt
Hypertension has become a prominent public health concern. Essential hypertension (EH) is a polygenic disorder caused by multiple susceptibility genes. It has been previously shown that the purinergic P2Y2 receptor (P2Y2R) regulates blood pressure; however, whether P2Y2R genetic polymorphisms correlate with EH has not been investigated in Chinese. Our study included 500 EH cases and 504 controls who are Chinese...
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