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Article

Association of P2X7 receptor genetic polymorphisms and expression with rheumatoid arthritis susceptibility in a sample of the Iranian population: a case-control study.

Clinical rheumatology - 1 Aug 2021

Bahari Gholamreza, Tabasi Farhad, Hashemi Mohammad, Zakeri Zahra, Taheri Mohsen

Abstract excerpt

OBJECTIVE: Rheumatoid arthritis (RA) is a complex inflammatory autoimmune disease with joint eruption, systemic manifestation, and numerous predisposing genetic factors. The P2X7 receptor is an essential ligand-gated channel that contributes to many physiological processes, especially inflammation. However, genetic variations can alter the P2X7 receptor function. Therefore, the present study aimed to explore the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Purinergic P2X7

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PMID: 33580375
DOI: 10.1007/s10067-021-05645-3

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