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Article

APOE Genotype and Nonrespiratory Sleep Parameters in Cognitively Intact Older Adults.

Sleep - 1 Aug 2017

Spira Adam P, An Yang, Peng Yu, Wu Mark N, Simonsick Eleanor M, Ferrucci Luigi, Resnick Susan M

Abstract excerpt

Study Objectives: The apolipoprotein E (APOE) Ɛ4 allele increases Alzheimer's disease (AD) risk and has been linked to a greater risk of sleep-disordered breathing. We investigated the association of APOE genotype with nonrespiratory sleep parameters. Methods: We studied 1264 cognitively normal participants in the Baltimore Longitudinal Study of Aging (mean = 57.5 ± 16.1 years, range 19.9-92.0, 48.2% women, 19.8%...

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Source

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Identifiers

PMID: 28482100
DOI: 10.1093/sleep/zsx076
PMCID: PMC5804995

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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