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Article

The Role of Amyloid, Tau, and APOE Genotype on the Relationship Between Informant-Reported Sleep Disturbance and Alzheimer's Disease Risks.

Journal of Alzheimer's disease : JAD - 1 Jan 2022

Kim Hyun, Levine Alina, Cohen Daniel, Gehrman Philip, Zhu Xi, Devanand Davangere P, Lee Seonjoo, Goldberg Terry E

Abstract excerpt

BACKGROUND: The association between sleep and Alzheimer's disease (AD) biomarkers are well-established, but little is known about how they interact to change the course of AD. OBJECTIVE: To determine the potential interaction between sleep disturbance and Aβ, tau, and APOE4 on brain atrophy and cognitive decline. METHODS: Sample included 351 participants (mean age 72.01 ± 6.67, 50.4%female) who were followed for...

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Share to Amyloid beta-Peptides
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35491776
DOI: 10.3233/JAD-215417
PMCID: PMC9644449

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