Article
Greater Cognitive Deficits with Sleep-disordered Breathing among Individuals with Genetic Susceptibility to Alzheimer Disease. The Multi-Ethnic Study of Atherosclerosis.
Annals of the American Thoracic Society - 1 Nov 2017
Johnson Dayna A, Lane Jacqueline, Wang Rui, Reid Michelle, Djonlagic Ina, Fitzpatrick Annette L, Rapp Stephen R, Charles Luenda E, O'Hara Ruth, Saxena Richa, Redline Susan
Abstract excerpt
RATIONALE: There are conflicting findings regarding the link between sleep apnea and cognitive dysfunction. OBJECTIVES: Investigate associations between indicators of sleep-disordered breathing (SDB) and cognitive function in the Multi-Ethnic Study of Atherosclerosis and assess effect modification by the apolipoprotein ε-4 (APOE-ε4) allele. METHODS: A diverse population (N = 1,752) underwent type 2 in-home...
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