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Article

Associations between depression, sleep disturbance, and apolipoprotein E in the development of Alzheimer's disease: dementia.

International psychogeriatrics - 1 Sept 2016

Burke Shanna L, Maramaldi Peter, Cadet Tamara, Kukull Walter

Abstract excerpt

BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative brain disease that causes cognitive impairment and dementia. Within the US, AD is the most common form of dementia in the elderly, affecting 1 in 10 people over the age of 65. Sleep disturbance has been called a "public health epidemic" and, like depression, is a prodromal symptom of AD but may also contribute to the risk of developing AD. It was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27020605
DOI: 10.1017/S1041610216000405
PMCID: PMC4963299

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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