Interaction between sleep-disordered breathing and apolipoprotein E genotype on cerebrospinal fluid biomarkers for Alzheimer's disease in cognitively normal elderly individuals.

doi:10.1016/j.neurobiolaging.2013.12.030

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Interaction between sleep-disordered breathing and apolipoprotein E genotype on cerebrospinal fluid biomarkers for Alzheimer's disease in cognitively normal elderly individuals.

Neurobiology of aging - 1 Jun 2014

Osorio Ricardo S, Ayappa Indu, Mantua Janna, Gumb Tyler, Varga Andrew, Mooney Anne M, Burschtin Omar E, Taxin Zachary, During Emmanuel, Spector Nicole, Biagioni Milton, Pirraglia Elizabeth, Lau Hiuyan, Zetterberg Henrik, Blennow Kaj, Lu Shou-En, Mosconi Lisa, Glodzik Lidia, Rapoport David M, de Leon Mony J

Abstract excerpt

Previous studies have suggested a link between sleep disordered breathing (SDB) and dementia risk. In the present study, we analyzed the relationship between SDB severity, cerebrospinal fluid (CSF) Alzheimer's disease-biomarkers, and the ApoE alleles. A total of 95 cognitively normal elderly participants were analyzed for SDB severity, CSF measures of phosphorylated-tau (p-tau), total-tau (t-tau), and amyloid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloid beta-Peptides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoprotein E4

Share to Cognitive Dysfunction

Share to Dementia

Share to Peptide Fragments

Share to Respiration

Share to Sleep Wake Disorders

Share to tau Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 24439479
DOI: 10.1016/j.neurobiolaging.2013.12.030
PMCID: PMC4022140

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between sleep-disordered breathing and apolipoprotein E genotype on cerebrospinal fluid biomarkers for Alzheimer's disease in cognitively normal elderly individuals.PMID 24439479Read ↗

How is sleep-disordered breathing linked with biomarkers of Alzheimer’s disease?Semantic proximity Read ↗

Greater Cognitive Deficits with Sleep-disordered Breathing among Individuals with Genetic Susceptibility to Alzheimer Disease. The Multi-Ethnic Study of Atherosclerosis.Semantic proximity Read ↗

Reduced rapid eye movement sleep in late middle-aged and older apolipoprotein E ɛ4 allele carriers.Semantic proximity Read ↗

Association between apolipoprotein E epsilon4 and sleep-disordered breathing in adults.Semantic proximity Read ↗

The Role of Amyloid, Tau, and APOE Genotype on the Relationship Between Informant-Reported Sleep Disturbance and Alzheimer's Disease Risks.Semantic proximity Read ↗

Sleep apnea, APOE4 and Alzheimer's disease 20 years and counting?Semantic proximity Read ↗

APOE Genotype and Nonrespiratory Sleep Parameters in Cognitively Intact Older Adults.Semantic proximity Read ↗

Association of Sleep Disturbances and Cognitive Decline among Cognitively Normal Elders Over TimeSemantic proximity Read ↗

APOE-ε4 synergizes with sleep disruption to accelerate Aβ deposition and Aβ-associated tau seeding and spreadingSemantic proximity Read ↗

The Effect of CPAP Intervention on Sleep Architecture and Cognition in Alzheimer’s Disease Patients with Obstructive Sleep ApneaSemantic proximity Read ↗

Non-linear and time-domain sleep qEEG features predict CSF protein damage markers in early Alzheimer’s diseaseSemantic proximity Read ↗

Unraveling the Mechanisms Underlying Disordered Sleep in Alzheimer's Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.