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Article

Apolipoprotein E ɛ4 (APOE ɛ4) Allele is Associated with Long Sleep Duration Among Elderly with Cognitive Impairment.

Journal of Alzheimer's disease : JAD - 1 Jan 2021

Basta Maria, Zaganas Ioannis, Simos Panagiotis, Koutentaki Eirini, Dimovasili Christina, Mathioudakis Lambros, Bourbouli Mara, Panagiotakis Symeon, Kapetanaki Stefania, Vgontzas Alexandros

Abstract excerpt

BACKGROUND: Apolipoprotein E gene (APOE) ɛ4 allele increases the risk for Alzheimer's disease (AD). Furthermore, among patients with cognitive impairment, longer sleep duration is associated with worse cognitive performance. To date, literature examining the associations between APOE ɛ4 allele and objective sleep duration is limited. OBJECTIVE: Our aim was to assess the association between APOE ɛ4 and objective...

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PMID: 33361595
DOI: 10.3233/JAD-200958

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