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Article

APOEε4 and slow wave sleep in older adults.

PloS one - 1 Jan 2018

Tranah Gregory J, Yaffe Kristine, Nievergelt Caroline M, Parimi Neeta, Glymour M Maria, Ensrud Kristine E, Cauley Jane A, Ancoli-Israel Sonia, Mariani Sara, Redline Susan, Stone Katie L

Abstract excerpt

Slow wave (or stage N3) sleep has been linked to a variety of cognitive processes. However, the role of stage N3 in the elderly is debated. The link between stage N3 and episodic memory may be weakened or changed in the older adult population, possibly due to several altered mechanisms impacting the cellular structure of the brain. The bases for the age-related dissociation between stage N3 and cognition are not...

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Identifiers

PMID: 29370207
DOI: 10.1371/journal.pone.0191281
PMCID: PMC5784964

Genes

APOE

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