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Article

Confirmation of involvement of new variants at CDKN2A/B in pediatric acute lymphoblastic leukemia susceptibility in the Spanish population.

PloS one - 1 Jan 2017

Gutierrez-Camino Angela, Martin-Guerrero Idoia, Garcia de Andoin Nagore, Sastre Ana, Carbone Bañeres Ana, Astigarraga Itziar, Navajas Aurora, Garcia-Orad Africa

Abstract excerpt

The locus CDKN2A/B (9p21.3), which comprises the tumor suppressors genes CDKN2A and CDKN2B and the long noncoding RNA (lncRNA) known as ANRIL (or CDKN2B-AS), was associated with childhood acute lymphoblastic leukemia (ALL) susceptibility in several genome wide association studies (GWAS). However, the variants associated in the diverse studies were different. Recently, new and independent SNPs deregulating the...

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PMID: 28481918
DOI: 10.1371/journal.pone.0177421
PMCID: PMC5421813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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