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Article

Putative functional variants of PI3K/AKT/mTOR pathway are associated with knee osteoarthritis susceptibility.

Journal of clinical laboratory analysis - 1 Jun 2020

Wang Kejie, Chu Minjie, Wang Feng, Zhao Yiwen, Chen Haifeng, Dai Xiaoyu

Abstract excerpt

BACKGROUND: Osteoarthritis (OA) is a degenerative musculoskeletal disease which causes joint deformity and pain and finally leads to limb dysfunction. Knee osteoarthritis (KOA) has the highest incidence among all kinds of OA. Strong evidence leads to the understanding that P13K/AKT/mTOR signaling is very important in cartilage degeneration. METHODS: This research sought to understand the association between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32052902
DOI: 10.1002/jcla.23240
PMCID: PMC7307371

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