Article
Contribution of the Akt2 gene to type 2 diabetes in the Chinese Han population.
Chinese medical journal - 1 Mar 2011
Sun Xiu-Qin, Luo Ying-Ying, An Ling-Wang, Chu Lin, Huo Li-Li, Han Xue-Yao, Zhou Xiang-Hai, Ren Qian, Ji Li-Nong
Abstract excerpt
BACKGROUND: The Akt2 protein kinase is thought to be a key mediator of the insulin signal transduction process. Akt2 is suggested to play a role in glucose metabolism and the development or maintenance of proper adipose tissue and islet mass. In order to determine whether the Akt2 gene plays a role in the pathogenesis of type 2 diabetes characterized by insulin resistance, and to further identify if variations in...
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