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Article

The genetic architecture in Saccharomyces cerevisiae that contributes to variation in drug response to the antifungals benomyl and ketoconazole.

FEMS yeast research - 1 May 2017

Roberts Christina A, Miller John H, Atkinson Paul H

Abstract excerpt

The genetic basis of variation in drug response was investigated in individual Saccharomyces cerevisiae strains that exhibited different susceptibility to two antifungal agents: benomyl and ketoconazole. Following dose-response screening of 25 strains, 4 were selected on the basis of resistance or sensitivity relative to the standard laboratory strain BY. UWOPS87-2421 and L-1374 were respectively resistant and...

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PMID: 28472279
DOI: 10.1093/femsyr/fox027

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