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Article

Harnessing gene expression to identify the genetic basis of drug resistance.

Molecular systems biology - 1 Jan 2009

Chen Bo-Juen, Causton Helen C, Mancenido Denesy, Goddard Noel L, Perlstein Ethan O, Pe'er Dana

Abstract excerpt

The advent of cost-effective genotyping and sequencing methods have recently made it possible to ask questions that address the genetic basis of phenotypic diversity and how natural variants interact with the environment. We developed Camelot (CAusal Modelling with Expression Linkage for cOmplex Traits), a statistical method that integrates genotype, gene expression and phenotype data to automatically build...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19888205
DOI: 10.1038/msb.2009.69
PMCID: PMC2779083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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