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Article

Allele-specific behavior of molecular networks: understanding small-molecule drug response in yeast.

PloS one - 1 Jan 2013

Zhang Fan, Gao Bo, Xu Liangde, Li Chunquan, Hao Dapeng, Zhang Shaojun, Zhou Meng, Su Fei, Chen Xi, Zhi Hui, Li Xia

Abstract excerpt

The study of systems genetics is changing the way the genetic and molecular basis of phenotypic variation, such as disease susceptibility and drug response, is being analyzed. Moreover, systems genetics aids in the translation of insights from systems biology into genetics. The use of systems genetics enables greater attention to be focused on the potential impact of genetic perturbations on the molecular states...

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Identifiers

PMID: 23308257
DOI: 10.1371/journal.pone.0053581
PMCID: PMC3537669

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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