Article
Conditional analysis of multiple quantitative traits based on marginal GWAS summary statistics.
Genetic epidemiology - 1 Jul 2017
Deng Yangqing, Pan Wei
Abstract excerpt
There has been an increasing interest in joint association testing of multiple traits for possible pleiotropic effects. However, even in the presence of pleiotropy, most of the existing methods cannot distinguish direct and indirect effects of a genetic variant, say single-nucleotide polymorphism (SNP), on multiple traits, and a conditional analysis of a trait adjusting for other traits is perhaps the simplest...
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